Azo compounds
Sigma Aldrich Fine Chemicals Biosciences Naphthol Blue Black Dye content 80 % | 1064-48-8 | MFCD00004017 | 100G
Naphthol Blue Black Dye content 80 % | Mol Wt: 616.49 | 1064-48-8 | MFCD00004017 | 100G
eMolecules Oakwood Chemicals Diisopropyl azodicarboxylate 1kg 480131280 044563 0 000 2446-83-5 MFCD00008875 202 210 C8H14N2O4
Oakwood Chemicals Diisopropyl azodicarboxylate 1kg 480131280 044563 0 000 2446-83-5 MFCD00008875 202 210 C8H14N2O4
Apexbio Technology LLC KW 2449 1000669-72-6 50mg
KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
Selleck Chemical LLC APG-2449-E1508-25MG
APG-2449 is an orally active inhibitor of ALK/ROS1/FAK APG-2449 exerts potent and durable antitumor activity in human non-small-cell lung cancer (NSCLC) and ovarian tumor models
Selleck Chemical LLC APG-2449-E1508-5MG
APG-2449 is an orally active inhibitor of ALK/ROS1/FAK APG-2449 exerts potent and durable antitumor activity in human non-small-cell lung cancer (NSCLC) and ovarian tumor models
Apexbio Technology LLC KW 2449 1000669-72-6 200mg
KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
Selleck Chemical LLC APG-2449-E1508-100MG
APG-2449 is an orally active inhibitor of ALK/ROS1/FAK APG-2449 exerts potent and durable antitumor activity in human non-small-cell lung cancer (NSCLC) and ovarian tumor models
Sigma Aldrich Fine Chemicals Biosciences Naphthol Blue Black BioReagent, suitable for electrophoresis | 1064-48-8 | MFCD00004017 | 25G
Naphthol Blue Black BioReagent, suitable for electrophoresis | Mol Wt: 616.49 | 1064-48-8 | MFCD00004017 | 25G
Medchemexpress LLC CAY 10465 50mg | 688348-33-6 | 98.3% | 317.13 | 50 MG
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
- Is a selective and high-affinity AhR receptor agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
- Reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells, and inhibits the synthesis of the protein (0.01 nM-100 μM).
Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 10 MG
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). It is intended for research use only. This compound has been shown to reduce apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibit protein synthesis.
- Selective and high-affinity AhR agonist
- Ki of 0.2 nM
- No effect on estrogen receptor (Ki >100000 nM)
- Reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells
- Inhibits protein synthesis
- Intended for research use only
Medchemexpress LLC KW-2449 | 1000669-72-6 | 99.9% | 332.40 | 10 MG
KW-2449 is a multi-targeted kinase inhibitor that targets FLT3, ABL, ABLT315I, and Aurora kinase with IC50 values of 6.6, 14, 4, and 48 nM, respectively. It is intended for research use only.
- Targets FLT3, ABL, ABLT315I, and Aurora kinase.
- Exhibits antiproliferative activity against imatinib-resistant K562 cells.
- Inhibits FLT3-mediated STAT5 phosphorylation.
- Increases G1 phase cells and promotes apoptosis.
- Suppresses tumor growth in FLT3-mutated xenograft models.
- Helps release imatinib resistance.
Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 1 ML
CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). This compound reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibits the synthesis of the protein.
- Selective and high-affinity AhR agonist
- No effect on estrogen receptor
- Reduces apolipoprotein A-I levels in HepG2 cells
- Inhibits protein synthesis